I'm experiencing the same issue on OSX 10.12.3. Synergy v1.8.8-stable-25a8cb2 works fine, but 1.9.0 rc3 crashes instantly when I try to start it.
Process: synergy [80543]
Path: /Volumes/VOLUME/*/Synergy.app/Contents/MacOS/synergy
Identifier: synergy
Version: 1.9.0 (1.9.0)
Code Type: X86-64 (Native)
Parent Process: ??? [1]
Responsible: synergy [80543]
User ID: 501
Date/Time: